Background: Many reports suggest that coil embolization (CE) is technically effective and safe to result in clinical improvement among patients with pelvic venous reflux (PVR). Some complications and adverse events of gonadal vein embolization with coils were published, including access-site hematoma, migration of coils, thrombosis of the parametrial/uterine veins, deep vein thrombosis of the leg, postembolization syndrome (PES), and protrusion of coils. Chronic pain related to protrusion of coils can be a challenging condition because it is resistant to medical treatment. Here, we report a case of persistent paraumbilical pain and chronic diarrhea as delayed adverse effects of CE of left ovarian vein. Case Presentation: A 47-year-old female patient suffered from chronic diarrhea and paraumbilical pain at the location of left ovarian vein. She received stenting of left renal vein and CE of left ovarian vein for nutcracker syndrome and PVR about 6 years ago. She called at gastroenterologist for help. The chronic diarrhea was controlled but the abdominal pain was persistent. After failing a 7-month conservative treatment including nonsteroidal anti-inflammatory drugs, antibiotics, and anticoagulant, she underwent robotic assisted left ovarian vein excision. Six weeks postoperatively, she reported no complications and great resolution of her chronic paraumbilical pain. Conclusions: According to Gavrilov et al. in 2022, the chronic pain related to protrusion of coils was resistant to the medicine. It must be resolved by excision of the gonadal vein with coils. PES related to CE of gonadal vein can be relieved by antibiotic and anticoagulant in our experience. Protrusion of coils can be a delayed adverse event after CE of gonadal veins.