Purpose: Diabetic foot ulcers are a common complication among the diabetic population. Current non-invasive therapy involves the use of specific dressings that have iodine or silver embedded within them. Narrandera is a rural town in southern New South Wales. 13% of the community are Indigenous, four times greater than the proportion Australia-wide. Multiple patients in Narrandera, many of whom are from Indigenous backgrounds, have reported the use of a medicinal plant colloquially referred to as Old Man Weed (OMW) for the treatment of diabetic foot wounds. However, it is unclear if clinical evidence supports its use. A scoping literature review was undertaken to explore the use of OMW as an alternative medicine in wound treatment. Additionally, we aim to describe the potential mechanisms behind its efficacy. Methodology: A scoping review was performed according to Arksey and O’Malley’s 5-step framework. A broad literature search was conducted using Embase, MEDLINE, CINAHL, Cochrane, Scopus and Google Scholar databases. Alternative search terms for OMW were also used. All types of English language peer-reviewed manuscripts, including editorials and author discussions, were reviewed. Results: Using the described search strategy, two papers were included. Both papers describe the use of OMW for medicinal purposes by the Aboriginal and Torres Strait Islander community in Australia. Additionally, both papers propose its antimicrobial properties can be attributed to its phenolic compounds. However, they differ in multiple factors such as its preparation, parts of the plant that can be used, as well as its specific uses. Conclusion: While OMW appears to have been widely used historically and has therapeutic biochemical components, further research is required. Additional research should be focused on identifying the method of application, and measuring outcomes of wounds with the use of this plant compared to existing wound therapies.